There are five different antidepressant classes: the selective serotonin reuptake inhibitors (SSRIs), the serotonin norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs), monoamine oxidase inhibitors (MAOIs), and the others class. See the TMAP Depression Manual (2008) for “the how to” on augmentation. See Texas Medication Algorithm Project Procedural Manual: Major Depressive Disorder Algorithm. And I wouldn’t add an SSRI to an SNRI or an SNRI to an SSRI. This is done in cases where the antidepressant clearly helps but the patient still has some depression symptoms while taking the maximum dose of the antidepressant.Īugmentation can be with another antidepressant from another antidepressant class except the monoamine oxidease inhibitors (MOAIs)–don’t add an MAOI. Other second-generation anti-psychotics are Zyprexa (olanzepin), Seroquel (quetiapine), and Risperdal (risperadone).Īugmentation is the addition of a second medicine to the patient’s antidepressant medicine. What the manufacturer is suggesting is that it be used as an augmentation strategy for non-psychotic (regular) depression, by far the most common kind.Įverything discussed today about Abilify applies to all the other drugs like it, called the second generation anti-psychotics (SGAs). It is used in the treatment of psychosis such as schizophrenia. Many people have seen the television ads for Abilify (aripiprazole) suggesting that you and your doctor consider adding it to your antidepressant to treat depression that has only partially responded to your antidepressant.Ībilify is a second-generation antipsychotic.
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